Stuart B. Levy, M.D. is Distinguished Professor of Molecular Biology and Microbiology and of Medicine at Tufts University School of Medicine; Director of the Center for Adaptation Genetics and Drug Resistance; and President of the International Alliance for Prudent Use of Antibiotics. Because of misuse and over-prescribing of antibiotics, bacteria quickly mutate to evade the force of antibiotics that used to cure infections and disease. As a result, many antibiotics are no longer effective, and the medical community is scrambling to manage the crisis. Dr. Stuart Levy was one of the first medical researchers to alert the scientific community and the public about the dangerous misuse and over-prescribing of antibiotics. Here, he discusses his uphill struggle over decades to raise the alert about the seriousness of the antibiotics "paradox" --the fact that bacteria easily mutate to escape the effectiveness of antibiotics. His 1992 book, The Antibiotic Paradox: How Miracle Drugs Are Destroying the Miracle, now in its second edition, has been translated into four languages.